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Health and Medicine
[ASAP] Development of Highly Potent, G-Protein Pathway Biased, Selective, and Orally Bioavailable GPR84 Agonists
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Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.3c00951
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December 26, 2023
[ASAP] A Mitochondria-Targeted NIR-II Molecule Fluorophore for Precise Cancer Phototheranostics
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Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.3c01677
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December 26, 2023
[ASAP] Novel 2-(5-Arylthiophen-2-yl)-benzoazole Cyclometalated Iridium(III) dppz Complexes Exhibit Selective Phototoxicity in Cancer Cells by Lysosomal Damage and Oncosis
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Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.3c01978
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December 23, 2023
[ASAP] Guiding the Way: Traditional Medicinal Chemistry Inspiration for Rational Gram-Negative Drug Design
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Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.3c01831
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December 22, 2023
[ASAP] Pitfalls and Considerations in Determining the Potency and Mutant Selectivity of Covalent Epidermal Growth Factor Receptor Inhibitors
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Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.3c01502
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December 22, 2023
[ASAP] Proline-Hinged α-Helical Peptides Sensitize Gram-Positive Antibiotics, Expanding Their Physicochemical Properties to Be Used as Gram-Negative Antibiotics
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Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.3c01473
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December 21, 2023
[ASAP] Halogenated Rocaglate Derivatives: Pan-antiviral Agents against Hepatitis E Virus and Emerging Viruses
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Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.3c01357
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December 21, 2023
[ASAP] Synthesis of Pyrazole-Based Macrocycles Leads to a Highly Selective Inhibitor for MST3
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Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.3c01980
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December 21, 2023
[ASAP] Discovery of (2S)-N-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-3-(6-(4-cyanophenyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)-2-hydroxy-2-methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment
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Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.3c01417
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December 21, 2023
[ASAP] Identification of a Dual Autophagy and REV-ERB Inhibitor with in Vivo Anticancer Efficacy
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Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.3c01432
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December 20, 2023
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