Tag: Conception

  • Public funding for single embryo transfer cuts multifetal pregnancy rates in IVF

    Public funding for single embryo transfer cuts multifetal pregnancy rates in IVF

    [ad_1]

    In the era after the introduction of publicly funded in vitro fertilization (IVF) mandating elective single embryo transfer, the multifetal pregnancy rate decreased significantly for IVF, but the contribution of ovulation induction and intrauterine insemination (OI/IUI) to multifetal pregnancy still needs attention, according to a new study from ICES and Queen’s University. 

    Twins, triplets, and higher multifetal pregnancies are associated with some adverse outcomes in pregnancy and childbirth. Fertility treatments such as IVF and ovulation induction and intrauterine insemination (OI/IUI) are more likely to result in a multifetal pregnancy. In Canada, Ontario’s publicly funded fertility program mandated the use of elective single embryo transfer (eSET) in 2015. 

    In a new study from the journal JAMA Network Open, researchers evaluated the association between fertility treatment and multifetal pregnancies in Ontario for over 1 million pregnancies between 2006 and 2021. This is one of the first studies to include all forms of fertility treatments and accounted for fetal reductions that may have been performed earlier in a pregnancy. 

    While we found a substantial decrease in multifetal pregnancy rates for IVF after the mandate was introduced, we didn’t see the same decrease after OI/IUI. It’s more difficult to regulate multifetal pregnancies with this type of fertility treatment, because the type of protocols used and adherence to specific cancellation criteria may differ across clinics.” 

    Maria Velez, lead author, adjunct scientist at ICES and associate professor in the department of Obstetrics and Gynaecology at Queen’s University

    Of the total number of pregnancies, 96.9% were from unassisted conception, 1.4% from OI/IUI and 1.7% from IVF. Compared to those who had unassisted conception, people who received fertility treatments tended to be older, lived in higher-income communities, and had more preexisting health conditions. 

    The overall rate of multifetal pregnancies declined from 2006 to 2021, but the decrease was greater for IVF pregnancies than for those conceived by OI/IUI. When comparing the time periods before and after the eSET mandate, the rate of multifetal pregnancies declined from 13% to 9% with OI/IUI, and from 29% to 7% with IVF. 

    Improvements in assisted reproductive technology (ART) have also influenced rates of multifetal pregnancies. Advances in technologies such as embryo culture media and elective freezing of all available embryos means higher success rates for pregnancy. 

    However, the authors say that “Future studies should address the cost-effectiveness of providing 1 vs multiple publicly funded IVF cycles, especially because some couples in Ontario still pursue privately paid IVF cycles, which can result in a higher rate of multifetal pregnancy and an inherently higher risk of maternal and neonatal morbidity.” 

    One limitation of the study was the lack of detail about those who underwent fetal reduction. The data also did not capture information about the type of medication used for OI/IUI, and IVF cycles would have included both private and publicly funded treatments. 

    Nevertheless, the findings show that changes to assisted reproductive technology and the introduction of a publicly funded IVF program in Ontario both contributed to a decrease in the risk of multifetal pregnancy. 

    “Future work should address the higher risk associated with OI/IUI, and changes may be needed to standardize protocols and cancellation policies,” says Velez. 

    Source:

    Journal reference:

    Velez, M. P., et al. (2024). Multifetal Pregnancy After Implementation of a Publicly Funded Fertility Program. JAMA Network Open. doi.org/10.1001/jamanetworkopen.2024.8496.

    [ad_2]

    Source link

  • Driver’s license laws for undocumented immigrants linked to improved birth outcomes

    Driver’s license laws for undocumented immigrants linked to improved birth outcomes

    [ad_1]

    In 2023, Rhode Island, Massachusetts and Minnesota joined a growing list of states that allow undocumented immigrants to obtain driver’s licenses if an applicant can provide certain documentation, such as a foreign birth certificate or passport and evidence of current residency in the state. Altogether, 19 states and the District of Columbia have similar legislation in place. And lawmakers in other states, such as Michigan and Oklahoma, have introduced similar legislation.

    In many cases, these laws were passed based on the premise that they would keep the roads safer by allowing undocumented immigrants to drive legally and obtain insurance. But new research from Washington University in St. Louis provides evidence that these laws also indirectly improve the overall health and well-being of immigrant mothers and their babies.

    The research, published Feb. 26 in the Journal of Health and Social Behavior, found that implementing license laws is associated with improvements in birth weight -; a critical measure of early development with long-term health implications -; for babies born to Mexican and Central American immigrants.

    The authors also noted a decline in preterm birth rates between 2008-2021 in states that enacted license laws compared with those that did not, though rates in both groups declined over time.

    Our study’s findings underscore how states’ extension of legal rights to immigrants can improve the health of the next generation.”


    Margot Moinester, study co-author and assistant professor of sociology in Arts & Sciences at WashU

    “Previous research has demonstrated that restrictive immigration policies and practices contribute to poor health outcomes for immigrant families, but our study is among the first to demonstrate a positive relationship between inclusive immigration policies and improved health.”

    Connecting the dots

    To study the connection between license laws and birth outcomes, Moinester and co-author Kaitlyn K. Stanhope, at Emory University, examined birth records for more than 4 million singleton births born to Mexican and Central American immigrants between 2008-2021 living in states that adopted these laws during the study period. They also tracked how many months prior to conception the law was implemented to assess how the relationship between the implementation of a license law and changes in perinatal health -; that of pregnant people and their babies before, during and after birth -; over time.

    Finally, as a control measure, they compared their findings with outcomes for U.S.-born, non-Hispanic white pregnant people living in these states, but found no correlation between the implementation of a license law and birth weight in this population.

    The research established a correlation between these laws and improved birth outcomes among babies born to Mexican and Central American immigrants, but stopped short of explaining why the correlation exists. According to Moinester and Stanhope, these laws likely influence perinatal health by lessening deportation fears and stress. It’s well known that stress prior to and during pregnancy can increase risk of adverse birth outcomes, including low birth weight and preterm birth.

    “By reducing the criminalization of immigrants, driver’s license laws may lessen deportation fears and subsequent stress, potentially improving birth outcomes,” Stanhope said.

    Because stress prior to conception -; not just during pregnancy -; can affect birth outcomes, it’s likely that the strength of the association would increase over time, she added.

    “While we see stress as one key mechanism through which these license laws may improve perinatal health, we also think it is possible that the laws could lead to improved birth outcomes by increasing immigrants’ access to financial resources, including better-paying jobs and more weekly work hours,” Moinester said.

    The authors also hypothesized that the laws would improve immigrants’ perinatal health by making it easier to access timely prenatal care. However, contrary to their hypothesis, they observed a slightly lower probability of first-trimester entry into care for individuals in states with license laws. According to the authors, one possible explanation could be that immigrants living in these states already had high rates of early prenatal care, meaning there was little room for improvement. Another possible explanation could be that access to a driver’s license was not enough to counteract other barriers, such as a lack of insurance, language differences and distance to care.

    Changing immigration landscape

    Over the past two decades, states have emerged as important players in the immigration policy arena, passing immigration legislation at a scale not seen in over a century, the authors said.

    “There’s been a lot of focus on the extreme measures taken by some states to keep immigrants out and limit their access to services and benefits, but many states have responded by affirming their support for immigrants,” Moinester said.

    “In fact, more than half of the states that have enacted license laws did so after 2015, when Donald Trump began his first campaign and made immigration enforcement a key issue.”

    According to Moinester, the findings from this study highlight the potential of an individual state policy to positively shape the lives of Mexican and Central American immigrants and their children amid a highly conflictual federal and state immigration policy climate.

    Because government-issued IDs are required to access a range of economic and material resources critical to health, including bank accounts, utilities, prescription medications, housing and safety net programs -; plus more job opportunities -; it’s likely these laws have other important health implications, Moinester said. More research is needed to better understand the health implications of these policies and to inform future policy decisions.

    [ad_2]

    Source link

  • If you’re poor, fertility treatment can be out of reach

    If you’re poor, fertility treatment can be out of reach

    [ad_1]

    Mary Delgado’s first pregnancy went according to plan, but when she tried to get pregnant again seven years later, nothing happened. After 10 months, Delgado, now 34, and her partner, Joaquin Rodriguez, went to see an OB-GYN. Tests showed she had endometriosis, which was interfering with conception. Delgado’s only option, the doctor said, was in vitro fertilization.

    “When she told me that, she broke me inside,” Delgado said, “because I knew it was so expensive.”

    Delgado, who lives in New York City, is enrolled in Medicaid, the federal-state health program for low-income and disabled people. The roughly $20,000 price tag for a round of IVF would be a financial stretch for lots of people, but for someone on Medicaid — for which the maximum annual income for a two-person household in New York is just over $26,000 — the treatment can be unattainable.

    Expansions of work-based insurance plans to cover fertility treatments, including free egg freezing and unlimited IVF cycles, are often touted by large companies as a boon for their employees. But people with lower incomes, often minorities, are more likely to be covered by Medicaid or skimpier commercial plans with no such coverage. That raises the question of whether medical assistance to create a family is only for the well-to-do or people with generous benefit packages.

    “In American health care, they don’t want the poor people to reproduce,” Delgado said. She was caring full-time for their son, who was born with a rare genetic disorder that required several surgeries before he was 5. Her partner, who works for a company that maintains the city’s yellow cabs, has an individual plan through the state insurance marketplace, but it does not include fertility coverage.

    Some medical experts whose patients have faced these issues say they can understand why people in Delgado’s situation think the system is stacked against them.

    “It feels a little like that,” said Elizabeth Ginsburg, a professor of obstetrics and gynecology at Harvard Medical School who is president-elect of the American Society for Reproductive Medicine, a research and advocacy group.

    Whether or not it’s intended, many say the inequity reflects poorly on the U.S.

    “This is really sort of standing out as a sore thumb in a nation that would like to claim that it cares for the less fortunate and it seeks to do anything it can for them,” said Eli Adashi, a professor of medical science at Brown University and former president of the Society for Reproductive Endocrinologists.

    Yet efforts to add coverage for fertility care to Medicaid face a lot of pushback, Ginsburg said.

    Over the years, Barbara Collura, president and CEO of the advocacy group Resolve: The National Infertility Association, has heard many explanations for why it doesn’t make sense to cover fertility treatment for Medicaid recipients. Legislators have asked, “If they can’t pay for fertility treatment, do they have any idea how much it costs to raise a child?” she said.

    “So right there, as a country we’re making judgments about who gets to have children,” Collura said.

    The legacy of the eugenics movement of the early 20th century, when states passed laws that permitted poor, nonwhite, and disabled people to be sterilized against their will, lingers as well.

    “As a reproductive justice person, I believe it’s a human right to have a child, and it’s a larger ethical issue to provide support,” said Regina Davis Moss, president and CEO of In Our Own Voice: National Black Women’s Reproductive Justice Agenda, an advocacy group.

    But such coverage decisions — especially when the health care safety net is involved — sometimes require difficult choices, because resources are limited.

    Even if state Medicaid programs wanted to cover fertility treatment, for instance, they would have to weigh the benefit against investing in other types of care, including maternity care, said Kate McEvoy, executive director of the National Association of Medicaid Directors. “There is a recognition about the primacy and urgency of maternity care,” she said.

    Medicaid pays for about 40% of births in the United States. And since 2022, 46 states and the District of Columbia have elected to extend Medicaid postpartum coverage to 12 months, up from 60 days.

    Fertility problems are relatively common, affecting roughly 10% of women and men of childbearing age, according to the National Institute of Child Health and Human Development.

    Traditionally, a couple is considered infertile if they’ve been trying to get pregnant unsuccessfully for 12 months. Last year, the ASRM broadened the definition of infertility to incorporate would-be parents beyond heterosexual couples, including people who can’t get pregnant for medical, sexual, or other reasons, as well as those who need medical interventions such as donor eggs or sperm to get pregnant.

    The World Health Organization defined infertility as a disease of the reproductive system characterized by failing to get pregnant after a year of unprotected intercourse. It terms the high cost of fertility treatment a major equity issue and has called for better policies and public financing to improve access.

    No matter how the condition is defined, private health plans often decline to cover fertility treatments because they don’t consider them “medically necessary.” Twenty states and Washington, D.C., have laws requiring health plans to provide some fertility coverage, but those laws vary greatly and apply only to companies whose plans are regulated by the state.

    In recent years, many companies have begun offering fertility treatment in a bid to recruit and retain top-notch talent. In 2023, 45% of companies with 500 or more workers covered IVF and/or drug therapy, according to the benefits consultant Mercer.

    But that doesn’t help people on Medicaid. Only two states’ Medicaid programs provide any fertility treatment: New York covers some oral ovulation-enhancing medications, and Illinois covers costs for fertility preservation, to freeze the eggs or sperm of people who need medical treatment that will likely make them infertile, such as for cancer. Several other states also are considering adding fertility preservation services.

    In Delgado’s case, Medicaid covered the tests to diagnose her endometriosis, but nothing more. She was searching the internet for fertility treatment options when she came upon a clinic group called CNY Fertility that seemed significantly less expensive than other clinics, and also offered in-house financing. Based in Syracuse, New York, the company has a handful of clinics in upstate New York cities and four other U.S. locations.

    Though Delgado and her partner had to travel more than 300 miles round trip to Albany for the procedures, the savings made it worthwhile. They were able do an entire IVF cycle, including medications, egg retrieval, genetic testing, and transferring the egg to her uterus, for $14,000. To pay for it, they took $7,000 of the cash they’d been saving to buy a home and financed the other half through the fertility clinic.

    She got pregnant on the first try, and their daughter, Emiliana, is now almost a year old.

    Delgado doesn’t resent people with more resources or better insurance coverage, but she wishes the system were more equitable.

    “I have a medical problem,” she said. “It’s not like I did IVF because I wanted to choose the gender.”

    One reason CNY is less expensive than other clinics is simply that the privately owned company chooses to charge less, said William Kiltz, its vice president of marketing and business development. Since the company’s beginning in 1997, it has become a large practice with a large volume of IVF cycles, which helps keep prices low.

    At this point, more than half its clients come from out of state, and many earn significantly less than a typical patient at another clinic. Twenty percent earn less than $50,000, and “we treat a good number who are on Medicaid,” Kiltz said.

    Now that their son, Joaquin, is settled in a good school, Delgado has started working for an agency that provides home health services. After putting in 30 hours a week for 90 days, she’ll be eligible for health insurance.

    One of the benefits: fertility coverage.




    Kaiser Health NewsThis article was reprinted from khn.org, a national newsroom that produces in-depth journalism about health issues and is one of the core operating programs at KFF – the independent source for health policy research, polling, and journalism.

    [ad_2]

    Source link

  • What are your concerns about the possibility of having children? Survey of parenthood intentions for 16–18-year-old students

    What are your concerns about the possibility of having children? Survey of parenthood intentions for 16–18-year-old students

    [ad_1]

    In a recent study published in Human Fertility, researchers surveyed 16- to 18-year-old undergraduates about their plans to become parents in England.

    Study: Parenthood intentions of 16–18-year-olds in England: a survey of school students. Image Credit: Rawpixel.com/Shutterstock.com
    Study: Parenthood intentions of 16–18-year-olds in England: a survey of school students. Image Credit: Rawpixel.com/Shutterstock.com

    Background

    Teenagers’ perspectives on having children are critical for improving reproductive and sex education. Due to deficiencies in reproductive health and sex education at school, they frequently underestimate their odds of conception and are unaware of age-related fertility consequences. Comprehensive reproductive health and sex education are critical for health and well-being since they reduce misconceptions and allow young individuals to make educated decisions throughout their reproductive lives.

    In the United Kingdom (UK), the biology curriculum does not address vital reproductive health subjects, and knowing teenagers’ attitudes about reproduction is critical for improving the existing relationships and sex education (RSE) curriculum.

    About the study

    In the present study, researchers questioned secondary school students aged between 16 and 18 years about their opinions on having children.

    Using the Department of Education’s database of all secondary schools in England, personal and professional relationships, and a tutor forum, the team contacted the schools and invited them to participate in the survey-based study. The 47-component online anonymous survey, which included open-ended and multiple-choice questions about demographic parameters, sex and reproduction knowledge and education, and attitudes about the potential of giving birth, was available from May 10, 2021, to July 18, 2022. The sample population consisted of 931 students.

    The researchers developed questions after reviewing the RSE syllabus of England using past survey approaches. They used skip logic, guiding particular students to questions based on past responses. They conducted cognitive interviews and discussed with research professionals on the subject to determine the reliability of the questions and alternatives listed in the survey.

    The team conducted one-on-one cognitive interviews with the targeted audience online, and five students (four men and one female) met the qualifying criteria. During the interview sessions, they used concurrent probing and think-aloud approaches, and all five participants piloted the study survey so that researchers could check the suitability of the survey structure, questions, and alternatives. The team modified the questions and answer choices depending on the input after each interview. They refined the questions by consulting with other reproductive health experts who had previously created comparable surveys.

    The team reviewed qualitative replies multiple times to become acquainted with the content, found the initial codes, and organized them into pertinent topics. They thoroughly analyzed and named the themes. The primary researcher led the analysis, which included discussions regarding theme allocation. Some pupils provided brief remarks, but most submitted lengthy ones. They analyzed qualitative data thematically and used descriptive statistics and chi-squared tests to examine quantitative data.

    Results

    Among the participants, 64% wanted to be parents, and 49% planned to have two children. Students preferring not to be a parent cite the world’s unstable and unsettled state, parental anxiety, the belief that children are unnecessary, and unpleasant connections with gestation and delivery. A few female participants were concerned about the challenges and risks of pregnancy and childbirth, thinking that the procedure would permanently harm their bodies and have a negative influence on their psychological well-being afterward.

    Many students (45%) were apprehensive about having children, citing fears about their capacity to have healthy children and the life their children could lead. The team identified the following six themes in their replies to the question on motherhood concerns: worries, self-doubt, health and well-being, significant investment, impediments to personal objectives, and non-inclusiveness for lesbian, gay, bisexual, and transgender (LGBTQ+) education.

    Students questioned their abilities to be good parents, reflecting fear and self-doubt of being labeled as bad parents. They believed that becoming a parent would entail several financial and emotional commitments for which they were unprepared. Some students with hereditary medical issues were concerned about becoming parents since they did not want their offspring to inherit their conditions.

    For several reasons, some students choose adoption over having their children. Some people stated anxiety about pregnancy and labor, and they wished to adopt it to prevent the mental and physical strains of it. Students from the LGBTQ+ category considered adoption a more feasible choice for having children than using expensive aided reproductive techniques. Students frequently dread having children by mistake because they lack awareness regarding conception rates and abortion methods. They are also concerned about their spouse leaving or filing for divorce after having children and the likelihood that their offspring would have impairments, genetic disorders, be unhealthy, or be LGBT.

    Conclusion

    Overall, the study findings revealed the parenting concerns of 16- to 18-year-old English school students, emphasizing the necessity for a specialized reproductive health and sex education program. Fears and uncertainties about motherhood impact their decision-making, with many female students expressing disinterest owing to pregnancy and delivery issues. Inadequate fertility education increases students’ unfavorable views regarding reproduction. The study recommends interdisciplinary training focusing on climate and biological interconnections to emphasize fertility rates and resources.

    [ad_2]

    Source link