Tag: Mitophagy

  • Kondadi, A. K., Anand, R. & Reichert, A. S. Cristae membrane dynamics – a paradigm change. Trends Cell Biol. 30, 923–936 (2020).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Soubannier, V. et al. A vesicular transport pathway shuttles cargo from mitochondria to lysosomes. Curr. Biol. 22, 135–141 (2012).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Li, X. et al. Mitochondria shed their outer membrane in response to infection-induced stress. Science 375, eabi4343 (2022).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Jiao, H. et al. Mitocytosis, a migrasome-mediated mitochondrial quality-control process. Cell 184, 2896–2910 (2021).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Ma, X. Mitochondria-lysosome-related organelles mediate mitochondrial clearance during cellular dedifferentiation. Cell Rep. 42, 113291 (2023).

  • Hughes, A. L., Hughes, C. E., Henderson, K. A., Yazvenko, N. & Gottschling, D. E. Selective sorting and destruction of mitochondrial membrane proteins in aged yeast. eLife 5, e13943 (2016).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Wolf, D. M. et al. Individual cristae within the same mitochondrion display different membrane potentials and are functionally independent. EMBO J. 38, e101056 (2019).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kondadi, A. K. et al. Cristae undergo continuous cycles of membrane remodelling in a MICOS‐dependent manner. EMBO Rep. 21, e49776 (2020).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Cogliati, S., Enriquez, J. A. & Scorrano, L. Mitochondrial cristae: where beauty meets functionality. Trends Biochem. Sci. 41, 261–273 (2016).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Correia-Melo, C., Ichim, G., G Tait, S. W. & Passos, F. Depletion of mitochondria in mammalian cells through enforced mitophagy. Nat. Protoc. 12, 183–194 (2016).

    Article 
    PubMed 

    Google Scholar
     

  • Stephan, T. et al. MICOS assembly controls mitochondrial inner membrane remodeling and crista junction redistribution to mediate cristae formation. EMBO J. 39, e104105 (2020).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Sugiura, A., McLelland, G., Fon, E. A. & McBride, H. M. A new pathway for mitochondrial quality control: mitochondrial‐derived vesicles. EMBO J. 33, 2142–2156 (2014).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • König, T. et al. MIROs and DRP1 drive mitochondrial-derived vesicle biogenesis and promote quality control. Nat. Cell Biol. 23, 1271–1286 (2021).

    Article 
    ADS 
    PubMed 

    Google Scholar
     

  • Matheoud, D. et al. Parkinson’s disease-related proteins PINK1 and Parkin repress mitochondrial antigen presentation. Cell 166, 314–327 (2016).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Schuler, M. H. et al. Mitochondrial-derived compartments facilitate cellular adaptation to amino acid stress. Mol. Cell 81, 3786–3802 (2021).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Lyamzaev, K. G. et al. MitoCLox: a novel mitochondria-targeted fluorescent probe for tracing lipid peroxidation. Oxid. Med. Cell. Longev. 2019, 9710208 (2019).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Lyamzaev, K. G. et al. Novel fluorescent mitochondria-targeted probe MitoCLox reports lipid peroxidation in response to oxidative stress in vivo. Oxid. Med. Cell. Longev. 2020, 3631272 (2020).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • McArthur, K. et al. BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis. Science 359, eaao6047 (2018).

    Article 
    PubMed 

    Google Scholar
     

  • Xian, H. et al. Oxidized DNA fragments exit mitochondria via mPTP- and VDAC-dependent channels to activate NLRP3 inflammasome and interferon signaling. Immunity 55, 1370–1385 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kim, J. et al. VDAC oligomers form mitochondrial pores to release mtDNA fragments and promote lupus-like disease. Science 366, 1531–1536 (2019).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Zecchini, V. et al. Fumarate induces vesicular release of mtDNA to drive innate immunity. Nature 615, 499–506 (2023).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Newman, L. E. et al. Mitochondrial DNA replication stress triggers a pro-inflammatory endosomal pathway of nucleoid disposal. Nat. Cell Biol. 26, 194–206 (2024).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • D’Aco, K. E. et al. Mitochondrial tRNA(Phe) mutation as a cause of end-stage renal disease in childhood. Pediatr. Nephrol. 28, 515–519 (2013).

    Article 
    PubMed 

    Google Scholar
     

  • Piper, R. C. & Katzmann, D. J. Biogenesis and function of multivesicular bodies. Annu. Rev. Cell Dev. Biol. 23, 519–547 (2007).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Shelke, G. V., Williamson, C. D., Jarnik, M. & Bonifacino, J. S. Inhibition of endolysosome fusion increases exosome secretion. J. Cell Biol. 222, e202209084 (2023).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kleele, T. et al. Distinct fission signatures predict mitochondrial degradation or biogenesis. Nature 593, 435–439 (2021).

    Article 
    ADS 
    CAS 
    PubMed 

    Google Scholar
     

  • Hoogenboom, B. W., Suda, K., Engel, A. & Fotiadis, D. The supramolecular assemblies of voltage-dependent anion channels in the native membrane. J. Mol. Biol. 370, 246–255 (2007).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Gonçalves, R. P., Buzhynskyy, N., Prima, V., Sturgis, J. N. & Scheuring, S. Supramolecular assembly of VDAC in native mitochondrial outer membranes. J. Mol. Biol. 369, 413–418 (2007).

    Article 
    PubMed 

    Google Scholar
     

  • Keinan, N., Tyomkin, D. & Shoshan-Barmatz, V. Oligomerization of the mitochondrial protein voltage-dependent anion channel is coupled to the induction of apoptosis. Mol. Cell. Biol. 30, 5698–5709 (2010).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Shteinfer-Kuzmine, A. et al. Targeting the mitochondrial protein VDAC1 as a potential therapeutic strategy in ALS. Int. J. Mol. Sci. 23, 9946 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Peng, W., Wong, Y. C. & Krainc, D. Mitochondria-lysosome contacts regulate mitochondrial Ca2+ dynamics via lysosomal TRPML1. Proc. Natl Acad. Sci. USA 117, 19266–19275 (2020).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Zhang, X. et al. MCOLN1 is a ROS sensor in lysosomes that regulates autophagy. Nat. Commun. 7, 12109 (2016).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Rossi, A., Pizzo, P. & Filadi, R. Calcium, mitochondria and cell metabolism: a functional triangle in bioenergetics. Biochim. Biophys. Acta Mol. Cell. Res. 1866, 1068–1078 (2019).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Dayam, R. M., Saric, A., Shilliday, R. E. & Botelho, R. J. The phosphoinositide-gated lysosomal Ca2+ channel, TRPML1, is required for phagosome maturation. Traffic 16, 1010–1026 (2015).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Chen, C. C. et al. A small molecule restores function to TRPML1 mutant isoforms responsible for mucolipidosis type IV. Nat. Commun. 5, 4681 (2014).

    Article 
    ADS 
    CAS 
    PubMed 

    Google Scholar
     

  • Dikic, I. & Elazar, Z. Mechanism and medical implications of mammalian autophagy. Nat. Rev. Mol. Cell Biol. 19, 349–364 (2018).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Kaushik, S. & Cuervo, A. M. The coming of age of chaperone-mediated autophagy. Nat. Rev. Mol. Cell Biol. 19, 365–381 (2018).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Wang, L., Klionsky, D. J. & Shen, H. M. The emerging mechanisms and functions of microautophagy. Nat. Rev. Mol. Cell Biol. 24, 186–203 (2023).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Müller, O. et al. Autophagic tubes: vacuolar invaginations involved in lateral membrane sorting and inverse vesicle budding. J. Cell Biol. 151, 519–528 (2000).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Oku, M. et al. Evidence for ESC RT- and clathrin-dependent microautophagy. J. Cell Biol. 216, 3263–3274 (2017).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Omari, S. et al. Noncanonical autophagy at ER exit sites regulates procollagen turnover. Proc. Natl Acad. Sci. USA 115, E10099–E10108 (2018).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Lee, C., Lamech, L., Johns, E. & Overholtzer, M. Selective lysosome membrane turnover is induced by nutrient starvation. Dev. Cell 55, 289–297 (2020).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Bento, C. F. et al. Mammalian autophagy: how does it work? Annu. Rev. Biochem. 85, 685–713 (2016).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Pickles, S., Vigi, P. & Youle, R. J. Current biology review mitophagy and quality control mechanisms in mitochondrial maintenance. Curr. Biol. 28, R170–R185 (2018).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kuchitsu, Y. & Taguchi, T. Lysosomal microautophagy: an emerging dimension in mammalian autophagy. Trends Cell Biol. 34, 606–616 (2023).

    Article 
    PubMed 

    Google Scholar
     

  • Palikaras, K., Lionaki, E. & Tavernarakis, N. Mechanisms of mitophagy in cellular homeostasis, physiology and pathology. Nat. Cell Biol. 20, 1013–1022 (2018).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Vietri, M., Radulovic, M. & Stenmark, H. The many functions of ESCRTs. Nat. Rev. Mol. Cell Biol. 21, 25–42 (2020).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Scheffer, L. L. et al. Mechanism of Ca2+-triggered ESCRT assembly and regulation of cell membrane repair. Nat. Commun. 5, 5646 (2014).

    Article 
    ADS 
    CAS 
    PubMed 

    Google Scholar
     

  • Huang, C., Deng, K. & Wu, M. Mitochondrial cristae in health and disease. Int. J. Biol. Macromol. 235, 123755 (2023).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Tábara, L. C. et al. MTFP1 controls mitochondrial fusion to regulate inner membrane quality control and maintain mtDNA levels. Cell 187, 3619–3637 (2024).

  • Elia, N., Sougrat, R., Spurlin, T. A., Hurley, J. H. & Lippincott-Schwartz, J. Dynamics of endosomal sorting complex required for transport (ESCRT) machinery during cytokinesis and its role in abscission. Proc Natl Acad. Sci. USA 108, 4846–4851 (2011).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Bagshaw, R. D., Callahan, J. W. & Mahuran, D. J. The Arf-family protein, Arl8b, is involved in the spatial distribution of lysosomes. Biochem. Biophys. Res. Commun. 344, 1186–1191 (2006).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Cemma, M., Kim, P. K. & Brumell, J. H. The ubiquitin-binding adaptor proteins p62/SQSTM1 and NDP52 are recruited independently to bacteria-associated microdomains to target Salmonella to the autophagy pathway. Autophagy 7, 341–345 (2011).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Boutry, M. & Kim, P. K. ORP1L mediated PI(4)P signaling at ER-lysosome-mitochondrion three-way contact contributes to mitochondrial division. Nat. Commun. 12, 5354 (2021).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Law, K. B. et al. The peroxisomal AAA ATPase complex prevents pexophagy and development of peroxisome biogenesis disorders. Autophagy 13, 868–884 (2017).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Sargent, G. et al. PEX2 is the E3 ubiquitin ligase required for pexophagy during starvation. J. Cell Biol. 214, 677–690 (2016).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Wang, Y., Nartiss, Y., Steipe, B., McQuibban, G. A. & Kim, P. K. ROS-induced mitochondrial depolarization initiates PARK2/PARKIN-dependent mitochondrial degradation by autophagy. Autophagy 8, 1462–1476 (2012).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Roy, M., Itoh, K., Iijima, M. & Sesaki, H. Parkin suppresses Drp1-independent mitochondrial division. Biochem. Biophys. Res. Commun. 475, 283–288 (2016).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kageyama, Y. et al. Parkin‐independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain. EMBO J. 33, 2798–2813 (2014).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Fujita, N. et al. Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin. J. Cell Biol. 203, 115–128 (2013).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Yan, B. R. et al. C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy. Autophagy 18, 829–840 (2022).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Durkin, M., Qian, X., Popescu, N. & Lowy, D. Isolation of mouse embryo fibroblasts. Bio Protoc. 3, e908 (2013).

    Article 
    PubMed 

    Google Scholar
     

  • Paul-Gilloteaux, P. et al. eC-CLEM: flexible multidimensional registration software for correlative microscopies. Nat. Methods 14, 102–103 (2017).

[ad_2]

Source link

  • Mitochondrial transfer mediates endothelial cell engraftment through mitophagy

    [ad_1]

  • Nowbar, A. N., Gitto, M., Howard, J. P., Francis, D. P. & Al-Lamee, R. Mortality from ischemic heart disease. Circ. Cardiovasc. Qual. Outcomes 12, e005375 (2019).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Loffredo, F. & Lee, R. T. Therapeutic vasculogenesis. Circ. Res. 103, 128–130 (2008).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Melero-Martin, J. M. et al. Engineering robust and functional vascular networks in vivo with human adult and cord blood-derived progenitor cells. Circ. Res. 103, 194–202 (2008).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Beckman, J. A., Schneider, P. A. & Conte, M. S. Advances in revascularization for peripheral artery disease: revascularization in PAD. Circ. Res. 128, 1885–1912 (2021).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Carmeliet, P. & Jain, R. K. Molecular mechanisms and clinical applications of angiogenesis. Nature 473, 298 (2011).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Cooke, J. P. & Losordo, D. W. Modulating the vascular response to limb ischemia. Circ. Res. 116, 1561–1578 (2015).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Wang, K., Lin, R.-Z. & Melero-Martin, J. M. Bioengineering human vascular networks: trends and directions in endothelial and perivascular cell sources. Cell. Mol. Life Sci. 76, 421–439 (2019).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Islam, M. N. et al. Mitochondrial transfer from bone-marrow–derived stromal cells to pulmonary alveoli protects against acute lung injury. Nat. Med. 18, 759 (2012).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Hayakawa, K. et al. Transfer of mitochondria from astrocytes to neurons after stroke. Nature 535, 551 (2016).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Jain, R. K. Molecular regulation of vessel maturation. Nat. Med. 9, 685–693 (2003).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Andrae, J., Gallini, R. & Betsholtz, C. Role of platelet-derived growth factors in physiology and medicine. Gene Dev. 22, 1276–1312 (2008).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Rustom, A., Saffrich, R., Markovic, I., Walther, P. & Gerdes, H.-H. Nanotubular highways for intercellular organelle transport. Science 303, 1007–1010 (2004).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Zhang, Y. et al. iPSC-MSCs with high intrinsic MIRO1 and sensitivity to TNF-α yield efficacious mitochondrial transfer to rescue anthracycline-induced cardiomyopathy. Stem Cell Rep. 7, 749–763 (2016).

    Article 
    CAS 

    Google Scholar
     

  • Hase, K. et al. M-Sec promotes membrane nanotube formation by interacting with Ral and the exocyst complex. Nat. Cell Biol. 11, 1427–1432 (2009).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Kitani, T., Kami, D., Matoba, S. & Gojo, S. Internalization of isolated functional mitochondria: involvement of macropinocytosis. J. Cell. Mol. Med. 18, 1694–1703 (2014).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Youle, R. J. & Narendra, D. P. Mechanisms of mitophagy. Nat. Rev. Mol. Cell Biol. 12, 9–14 (2011).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Jin, S. M. & Youle, R. J. PINK1- and Parkin-mediated mitophagy at a glance. J. Cell Sci. 125, 795–799 (2012).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Liu, K. et al. Mesenchymal stem cells rescue injured endothelial cells in an in vitro ischemia–reperfusion model via tunneling nanotube like structure-mediated mitochondrial transfer. Microvasc. Res. 92, 10–18 (2014).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Liang, X. et al. Direct administration of mesenchymal stem cell‐derived mitochondria improves cardiac function after infarction via ameliorating endothelial senescence. Bioeng. Transl. Med. 8, e10365 (2023).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Borcherding, N. et al. Dietary lipids inhibit mitochondria transfer to macrophages to divert adipocyte-derived mitochondria into the blood. Cell Metab. 34, 1499–1513 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kami, D. & Gojo, S. From cell entry to engraftment of exogenous mitochondria. Int. J. Mol. Sci. 21, 4995 (2020).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Elliott, R. L., Jiang, X. P. & Head, J. F. Mitochondria organelle transplantation: introduction of normal epithelial mitochondria into human cancer cells inhibits proliferation and increases drug sensitivity. Breast Cancer Res. Treat. 136, 347–354 (2012).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Chang, J.-C. et al. Allogeneic/xenogeneic transplantation of peptide-labeled mitochondria in Parkinson’s disease: restoration of mitochondria functions and attenuation of 6-hydroxydopamine–induced neurotoxicity. Transl. Res. 170, 40–56 (2016).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Kaza, A. K. et al. Myocardial rescue with autologous mitochondrial transplantation in a porcine model of ischemia/reperfusion. J. Thorac. Cardiovasc. Surg. 153, 934–943 (2017).

    Article 
    PubMed 

    Google Scholar
     

  • Emani, S. M., Piekarski, B. L., Harrild, D., Del Nido, P. J. & McCully, J. D. Autologous mitochondrial transplantation for dysfunction after ischemia-reperfusion injury. J. Thorac. Cardiovasc. Surg. 154, 286–289 (2017).

    Article 
    PubMed 

    Google Scholar
     

  • Bertero, E., Maack, C. & O’Rourke, B. Mitochondrial transplantation in humans: “magical” cure or cause for concern? J. Clin. Invest. 128, 5191–5194 (2018).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Lightowlers, R. N., Chrzanowska‐Lightowlers, Z. M. & Russell, O. M. Mitochondrial transplantation—a possible therapeutic for mitochondrial dysfunction? EMBO Rep. 21, e50964 (2020).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Ashrafi, G. & Schwarz, T. L. The pathways of mitophagy for quality control and clearance of mitochondria. Cell Death Differ. 20, 31–42 (2013).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Moreau, K., Luo, S. & Rubinsztein, D. C. Cytoprotective roles for autophagy. Curr. Opin. Cell Biol. 22, 206–211 (2010).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Gao, Y. et al. Role of Parkin-mediated mitophagy in the protective effect of polydatin in sepsis-induced acute kidney injury. J. Transl. Med. 18, 114 (2020).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Livingston, M. J. et al. Clearance of damaged mitochondria via mitophagy is important to the protective effect of ischemic preconditioning in kidneys. Autophagy 15, 2142–2162 (2019).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Sun, Z. et al. MSC-derived extracellular vesicles activate mitophagy to alleviate renal ischemia/reperfusion injury via the miR-223-3p/NLRP3 axis. Stem Cells Int. 2022, 6852661 (2022).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Mahrouf-Yorgov, M. et al. Mesenchymal stem cells sense mitochondria released from damaged cells as danger signals to activate their rescue properties. Cell Death Differ. 24, 1224–1238 (2017).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Zhu, W. et al. Mesenchymal stem cells ameliorate hyperglycemia-induced endothelial injury through modulation of mitophagy. Cell Death Dis. 9, 837 (2018).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kim, M. J., Hwang, J. W., Yun, C.-K., Lee, Y. & Choi, Y.-S. Delivery of exogenous mitochondria via centrifugation enhances cellular metabolic function. Sci. Rep. 8, 3330 (2018).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Melero-Martin, J. M. et al. In vivo vasculogenic potential of human blood-derived endothelial progenitor cells. Blood 109, 4761–4768 (2007).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Lin, R.-Z. et al. Human endothelial colony-forming cells serve as trophic mediators for mesenchymal stem cell engraftment via paracrine signaling. Proc. Natl Acad. Sci. USA 111, 10137–10142 (2014).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • [ad_2]

    Source link