Browsing Tag
DNA damage and repair
4 posts
FANCD2–FANCI surveys DNA and recognizes double- to single-stranded junctions
Cloning and protein purification A codon-optimized construct of full-length Gallus gallus FANCD2 including a carboxyl-terminal double StrepII tag…
July 31, 2024
Transcription–replication conflicts underlie sensitivity to PARP inhibitors
Cell culture and drug treatments The human cervical cell line HeLa and the human osteosarcoma cell line U2OS…
March 20, 2024
Genetic determinants of micronucleus formation in vivo
Animals All experiments were performed in accordance with UK Home Office regulations and the UK Animals (Scientific Procedures)…
February 14, 2024
Translation selectively destroys non-functional transcription complexes
Proteins and nucleic acids Wild-type E. coli core RNAP was expressed from PVS10 plasmid coding for all five…
February 7, 2024