Browsing Tag
Genome evolution
7 posts
Normal breast tissues harbour rare populations of aneuploid epithelial cells
Curtis, C. et al. The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups. Nature 486,…
Recurrent evolution and selection shape structural diversity at the amylase locus
Amylase gene naming conventions The reference genome GRC38 represents an H3 haplotype with three copies of the AMY1…
The complete sequence and comparative analysis of ape sex chromosomes
Fan, Y. & Silber, S. J. in GeneReviews (eds Adam, M. P. et al.) (Univ. of Washington, Seattle,…
Emx2 underlies the development and evolution of marsupial gliding membranes
The P. breviceps sugar glider breeding colony All experiments performed were approved by the IACUC committee at Princeton…
The variation and evolution of complete human centromeres
Cell lines CHM1hTERT (CHM1) cells were originally isolated from a hydatidiform mole at Magee-Womens Hospital. Cryogenically frozen cells…
The complex polyploid genome architecture of sugarcane
Genome sequencing Illumina libraries Illumina libraries for this manuscript were sequenced on a combination of Illumina X10, HiSeq…
Synthetic reversed sequences reveal default genomic states
Design of synthetic loci The synthetic HPRT1 locus has been described previously18. The synthetic HPRT1R locus was designed…