Browsing Tag
Innate immunity
5 posts
AARS1 and AARS2 sense l-lactate to regulate cGAS as global lysine lactyltransferases
Zhang, D. et al. Metabolic regulation of gene expression by histone lactylation. Nature 574, 575–580 (2019). Article ADS …
September 25, 2024
Alternating high-fat diet enhances atherosclerosis by neutrophil reprogramming
Libby, P. The changing landscape of atherosclerosis. Nature 592, 524–533 (2021). Article ADS CAS PubMed Google Scholar Strohacker,…
September 4, 2024
Obesity induces PD-1 on macrophages to suppress anti-tumour immunity
Islami, F., Goding Sauer, A., Gapstur, S. M. & Jemal, A. Proportion of cancer cases attributable to excess…
June 12, 2024
Rapid unleashing of macrophage efferocytic capacity via transcriptional pause release
Morioka, S., Maueröder, C. & Ravichandran, K. S. Living on the edge: efferocytosis at the interface of homeostasis…
March 13, 2024
The CRL5–SPSB3 ubiquitin ligase targets nuclear cGAS for degradation
Cell culture HeLa (CCL-2) cells were obtained from Sigma-Aldrich. HEK293T cells were a gift from D. Trono (EPFL),…
February 28, 2024