Browsing Tag
Mouse Model
11 posts
Exploring how gene variants affect brain cells in children with severe epilepsy
Epilepsy is a brain disorder that causes recurring seizures. It is one of the most common neurological diseases,…
Researchers elucidate how gene mutation mechanism causes autism
Researchers show how mutations of gene transcription and chromatin regulation-related genes cause autism. The loss-of-function mutation of KMT2C, a…
Lactate’s role in driving cancer cachexia uncovered
A recent Nature Metabolism study reports that circulating lactate levels are positively associated with weight loss in cancer cachexia…
Mouse models shed light on the effects of metformin use during pregnancy on offspring
With the rise in gestational diabetes and metabolic disorders during pregnancy, metformin is also being prescribed more frequently.…
Limoncella apple polyphenol extract shines in IBD liver damage study
In a recent study published in the International Journal of Molecular Sciences, a group of researchers evaluated the…
New research identifies potential drug target to prevent kidney failure
A new study found that retinoic acid receptors (RARa) in the proximal tubules of the kidney play a…
Scientists transform skin cells into functional eggs in mice
New research from Oregon Health & Science University describes the science behind a promising technique to treat infertility…
Unlocking the secrets of T follicular helper cells for better treatment strategies
T follicular helper cells (Tfh) are essential for strong antibody-mediated reactions of our immune system during infections and…
Missing gut microbes after antibiotics and a high-fat diet may be to blame for sugar-free candy and gum giving you gas
In high-income countries, carbohydrate intolerance affects about 30% of the population. The exact mechanism of sorbitol intolerance remains…
Androgen receptor signaling found to upregulate gene driving melanoma severity in men
In a recent study published by Nature Communications, researchers uncovered a previously unknown method by which androgen-activated androgen…