Browsing Tag
Regeneration
11 posts
World-first stem-cell treatment restores vision in people
Three people with severely impaired vision who received stem-cell transplants have experienced substantial improvements in their sight that…
Disease background influences fate of transplanted stem cells
NEWS AND VIEWS 23 October 2024 Gene-edited stem cells can be used in regenerative therapies to treat diverse…
Intestinal tuft cells act as reserve stem cells after injury
RESEARCH BRIEFINGS 23 October 2024 The mechanisms that compensate for the loss of intestinal stem cells after injury…
CRISPR–Cas9 screens reveal regulators of ageing in neural stem cells
Laboratory animals Cas9-expressing mice (Cas9 mice) were obtained from the Jackson Laboratory (https://www.jax.org/strain/024858). These mice (background C57BL/6N) constitutively…
Tuft cells act as regenerative stem cells in the human intestine
Fetal and adult tissues Uninflamed ileum, duodenum and colon were obtained from patients undergoing tumour-resection surgery; tissues were…
Tissues stay fit by balancing clearance of dying cells with regeneration
RESEARCH BRIEFINGS 21 August 2024 Clearance of dying cells is essential to the health of tissues. Study of…
Acquisition of epithelial plasticity in human chronic liver disease
Ethics Biopsy collection and processing of human samples were carried out under ethics approval by Addenbrookes Hospital REC…
Airway hillocks are injury-resistant reservoirs of unique plastic stem cells
Montoro, D. T. et al. A revised airway epithelial hierarchy includes CFTR-expressing ionocytes. Nature 560, 319–324 (2018). Article …
Cells destroy donated mitochondria to build blood vessels
Nature, Published online: 01 May 2024; doi:10.1038/d41586-024-01233-y Organelles called mitochondria are transferred to blood-vessel-forming cells by support cells.…
Rat neurons repair mouse brains — and restore sense of smell
Two research teams have demonstrated that adding rat neurons to mouse brains that were missing crucial cells could…