Browsing Tag
Immunosurveillance
3 posts
The type 2 cytokine Fc–IL-4 revitalizes exhausted CD8+ T cells against cancer
Animals Six- to eight-week-old female CD45.2+Thy1.2+ C57BL/6 (C57BL/6J) mice, CD45.1+ mice (B6.SJL-Ptprca Pepcb/BoyCrl) and NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (NSG) mice…
September 25, 2024
Glycosphingolipid synthesis mediates immune evasion in KRAS-driven cancer
Ubellacker, J. M. et al. Lymph protects metastasizing melanoma cells from ferroptosis. Nature 585, 113–118 (2020). Article ADS …
August 7, 2024
SOX17 enables immune evasion of early colorectal adenomas and cancers
Pelka, K. et al. Spatially organized multicellular immune hubs in human colorectal cancer. Cell 184, 4734–4752.e4720 (2021). Article …
February 28, 2024