Browsing Tag
Neuroimmunology
16 posts
Macrophages excite muscle spindles with glutamate to bolster locomotion
Mice Animal work was conducted according to UK Home Office licence legislation under the Animals (Scientific Procedures) Act…
Genetic defects of brain immunity in childhood herpes simplex encephalitis
Gnann, J. W. Jr & Whitley, R. J. Herpes simplex encephalitis: an update. Curr. Infect. Dis. Rep. 19,…
Myocardial infarction augments sleep to limit cardiac inflammation and damage
St-Onge, M.-P. et al. Sleep duration and quality: impact on lifestyle behaviors and cardiometabolic health: a scientific statement…
Engineered T cell therapy for central nervous system injury
GBD 2016 Traumatic Brain Injury and Spinal Cord Injury Collaborators.Global, regional, and national burden of traumatic brain injury…
A γδ T cell–IL-3 axis controls allergic responses through sensory neurons
Perner, C. et al. Substance P release by sensory neurons triggers dendritic cell migration and initiates the type-2…
Fibrin drives thromboinflammation and neuropathology in COVID-19
Animals C57BL/6 mice and K18-hACE2 mice (strain: B6.Cg-Tg(K18-ACE2)2Prlmn/J) were purchased from the Jackson Laboratory. Fga−/− mice52 and Fggγ390–396A…
CGRP sensory neurons promote tissue healing via neutrophils and macrophages
Ethical statement for animal experiments Animal experiments were approved by the Monash Animal Research Platform ethics committee and…
Children with multiple sclerosis have better outcomes if treated early and with high-efficacy therapies
A ground-breaking study – the largest of its kind globally – has found children with multiple sclerosis (MS)…
Venous-plexus-associated lymphoid hubs support meningeal humoral immunity
Kipnis, J. Multifaceted interactions between adaptive immunity and the central nervous system. Science 353, 766–771 (2016). Article CAS …
Disease-associated astrocyte epigenetic memory promotes CNS pathology
Rothhammer, V. et al. Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous…